Cell Culture Shear Protection: Added at 0.1% Poloxamer 188 to protect suspension and adherent cells from shear stress in shaking flasks and bioreactors.

Viral Vector Production and Handling: Enhances cell viability and stabilizes AAV/Lentivirus during mixing, filtration, and storage at 0.1% Poloxamer 188.

Transduction and Transfection Workflows: Improves transduction efficiency and protects cells during reagent addition and agitation with 0.1% Poloxamer 188.

Protein and Enzyme Stabilization: Minimizes adsorption to plastics and reduces aggregation in assays and storage buffers using 0.1% Poloxamer 188.

Filtration and Chromatography: Reduces nonspecific binding and membrane/column fouling during clarification and purification with 0.1% Poloxamer 188.

Fermentation Antifoam: Controls foam in microbial and mammalian fermentations, including E. coli and Bacillus subtilis, at 0.1% Poloxamer 188.

Flow Cytometry and Cell Sorting: Limits cell clumping and adhesion to plasticware to improve recovery and signal quality using 0.1% Poloxamer 188.

Cryopreservation and Thawing: Enhances post-thaw recovery by mitigating membrane damage when included at 0.1% Poloxamer 188.

Nanoparticle and LNP Handling: Stabilizes particles and reduces surface loss during dilution, mixing, and filtration with 0.1% Poloxamer 188.