Products
Categories
Suggestions
Custom Order
FAQ

We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.

Research and Development

Our Research and Development team

We're working alongside you to develop novel products that remove obstacles in your gene therapy bioproduction workflow.

 

 

Explore our novel products Teknova x Sartorius BIA Separations See our latest findings

Innovating for the future of health

 

We're investing in the discovery of novel products designed to give you a competitive advantage in your work. With custom manufacturing capabilities that fit seamlessly into your cell and gene therapy workflow and our in-house scientific expertise, we can be a true partner to you, helping you overcome bioprocessing challenges and accelerate your breakthroughs.

By scientists, 
for scientists

We launched our Research and Development initiative in 2021, bringing together a talented team of scientists with diverse specialties including synthetic biology, cell line engineering and development, cloning, downstream processing, advanced analytics, and viral production. Our intimate understanding of your workflow helps us make solutions possible. 

 

Advancing AAV bioprocessing solutions

Our current focus is on supporting customers working in cell and gene therapy with our custom capabilities and products. To truly understand your specific challenges, we have outfitted our laboratory with a complete end-to-end solution for AAV production, purification, and analyses. This includes plasmid construction and scaleup, suspension-based viral production, a downstream processing suite with multiple AKTAs, and state of the art analytical instrumentation for total characterization.

Our novel products

We currently have two proprietary products in the final stages of development. An RNA-based reporter assay for AAV detection that improves on current infectivity tests, and an AEX buffer screening kit that allows customers to rapidly find their optimal buffer formulation for full capsid enrichment.


Our collaboration with 
Sartorius BIA Separations

Our research

 

Together, we conducted a robust design of experiments (DOE) and successfully created highly-customized buffer formulations that drive consistency and increased AAV purity when paired with the BIA CIMmultus® QA monolith.

 

The buffers and parameters discovered in this study were then further optimized to create our first-of-its-kind AAV·Tek AEX Buffer Screening Kit, which is now available for AAV2 and AAV8.

 

 


See the data

Our collaborative research shows the successful achievement of over 85% full AAV capsid enrichment with 80-90% recoveries when pairing optimized equilibration and elution buffers from our AAV·Tek AEX Buffer Screening Kit with Sartorius BIA Separations' BIA CIMmultus® QA monolith at the polishing step, given a specific starting material of AAV8 that contained 46% full capsids.

 

Watch our webinar to see the detailed results of the study.

 

See our results

THE POWER OF PARTNERSHIP

Working together to
make solutions possible

“Our collaboration with Teknova has demonstrated two essential components for the successful separation of AAV empty and full capsids during the downstream polishing step: the purification platform and the buffer composition. By combining our strengths, we’ve been able to consistently reproduce results that indicate the use of Teknova’s high-quality, custom buffer formulations with our CIMmultus QA monolith increases the yield and purity of full AAV particles.”

 

- Aleš Štrancar, Managing Director at Sartorius BIA Separations

 

 

Interested in trying our AAV Reporter Assay?

Join our Early Access Program to get advance access to our novel products, including our AAV Reporter Assay and AEX screening solutions for additional serotypes. Email us at research@teknova.com to learn more.

Email our team

Join our Early Access Program

 

We are actively looking for partners to participate in our Early Access Program. You'll gain exclusive access to our AAV Reporter Assay and additional AEX buffer screening solutions (including AAV6, AAV8, and AAV9) and have the opportunity to provide feedback that can shape their design.

Get in touch to learn more

Give us a call:

1.800.209.4488

Monday to Friday

8:00AM–5:00PM PT

Call

Did you know?

We have AAV production capabilities in-house, including plasmid cloning for research. If you are interested in AAV purification services, get in touch with our team to discuss.

Discover more about us

 

Our history
ABOUT US
Join our team
CAREERS
f
How we give back
COMMUNITY